The Charm-Pure™ gDNA Isolation Kit (Tissues and Cells) is designed and optimized for easy and fast isolation of high-quality gDNA from tissues and cells. Charm-Pure system employs special turbo-binding membranes as selective nucleic acid captures in a familiar spin column format to efficiently extract gDNA from tissues and cells with higher yield and purity than conventional silica membrane. Genomic DNA molecules can specifically interact
with the turbo-binding membrane in the extraction buffer, while proteins and other
contaminants are not bound and remain in the solution and passed through. After washing the column with washing buffer to remove
unbound material, the purified gDNA can be easily eluted in 10 mM Tris Elution
Buffer or water and is ready for use in downstream applications,
such as restriction enzyme digestion, primer extension, PCR, whole genome
amplification (WGA) and other genomic analysis.